Relationship between obstructive sleep apnea syndrome and functional capacity in patients with diabetes mellitus type 2: an observational transversal study

SUMMARY OBJECTIVE: The aim of this study was to verify the association among obstructive sleep apnea, functional capacity, and metabolic control. METHODS: This was a cross-sectional study involving individuals of both sexes with clinical diagnosis of diabetes mellitus type 2 who were above 18 years of age. The assessment consisted of a volunteer identification form, a 2-minute step test, and the Stop-Bang questionnaire. In order to assess metabolic control, HbA1c and fasting glucose data were collected from medical records. RESULTS: A total of 100 individuals with diabetes mellitus type 2, of whom 61% were women, were included in this study. According to the Stop-Bang instrument, 26, 57, and 17% of patients had low, intermediate, and high risk of developing OSA, respectively. There was no association between the 2-minute step test and metabolic variables and diabetes mellitus type 2 chronicity with Stop-Bang. CONCLUSIONS: We concluded that there is no association among obstructive sleep apnea measured by means of Stop-Bang instrument, functional capacity measured by means of 2-minute step test, and metabolic variables in individuals with diabetes mellitus type 2.

Análise de zumbido em pacientes com diagnóstico de alça Vascular De VIII par craniano à ressonância nuclear magnética / Analysis of tinnitus in patients diagnosed with vascular loop of the viii cranial nerve on magnetic resonance imaging

Analisar e correlacionar sinais e sintomas auditivos, com ênfase no zumbido, achados audiológicos e sua incidência em indivíduos com alça vascular (AV) de VII/VIII par demonstrado por imagens de RNM de ângulo ponto cerebelar, classificando-os segundo Chavda. Estudo retrospectivo e transversal por meio da análise de dados clínicos dos prontuários de 15 pacientes, correlacionando queixas auditivas e otológicas com resultados encontrados nos exames complementares de Audiometria e RNM a que foram submetidos. Os pacientes que apresentavam alteração do trajeto dos vasos que penetram no MAI, formando alça vascular de VII e/ou VIII par craniano, foram classificados segundo Chavda. Todos os pacientes tinham exame de RNM com diagnóstico de alça vascular do VIII par. Onze deles (73,33%) eram bilaterais. Em 5 pacientes, houve concordância da queixa com os achados à RNM: sintomas bilaterais e alça vascular bilateral. O zumbido gerado pelas estruturas para-auditivas vasculares também são denominados zumbidos pulsáteis. Esses estados levam a fluxo turbulento, gerando o zumbido, que por sua vez é síncrono com o pulso do paciente. Há estudos demonstrando que não há correlação entre zumbido e contato vascular com o VIII par. Encontramos presença de zumbido em aproximadamente 80% dos pacientes com alça vascular, mas nem sempre a queixa coincidiu com a patologia, sendo difícil, portanto, correlacionar queixa e patologia. A presença de alça vascular na RNM não é patológica, mas um achado de exame. A presença do conflito neurovascular do VII/VIII par craniano nas imagens de RNM não justificou por si só os sinais e sintomas otoneurológicos e as al-terações audiovestibulares encontradas nos indivíduos avaliados neste estudo.

To analyze and correlate auditory signs and symptoms, emphasising tinnitus, audiological findings, and their incidence in individuals with vascular loop (AV) of VII/VIII pair demonstrated by MRI images of the cerebellopontine angle, classifying them according to Chavda. A retrospective and cross-sectional study by analyzing clinical data from the medical records of 15 patients, correlating hearing and otological complaints with results found in the complementary tests of Audiometry and MRI. Patients who presented alterations in the path of the vessels that penetrate the IAC, forming a vascular loop of the VII and/or VIII cranial nerve, were classified according to Chavda. All patients had an MRI with a vascular loop of the VIII pair diagnosed. Eleven of them (73.33%) were bilateral. In 5 patients, there was an agreement between the complaint and the MRI findings: bilateral symptoms and bilateral vascular loop. Tinnitus generated by vascular para-auditory structures is also called pulsatile tinnitus. These conditions lead to turbulent flow that causes tinnitus, synchronous with the patient's pulse. There are studies demonstrating there is no correlation between tinnitus and vascular contact with the VIII pair. We found the presence of tinnitus in approximately 80% of patients with vascular loop, but the complaint did not always coincide with the pathology, making it hard to correlate complaints and pathology. The presence of a vascular loop on MRI is not pathological but an examination finding. The neurovascular conflict of the VII/VIII cranial nerve present in the MRI images did not alone justify the otoneurological signs and symptoms and the audiovestibular alterations found in the individuals evaluated in this study.

Prevalência de apêndices préauriculares isolados em recémnascidos e resultados na triagem auditiva neonatal / Prevalence of isolated pre-auricular appendages in newborns and results in neonatal hearing screening

Introdução: os apêndices pré-auriculares, em conjunto com outras malformações craniofaciais e do osso temporal, estão associados à deficiência auditiva. Dentre as malformações do pavilhão auricular, encontram-se os apêndices pré-auriculares, formados por pele e cartilagem, e que podem estar presentes em qualquer ponto entre o trágus da orelha e o ângulo da boca, uni ou bilaterais. Objetivo: avaliar a resposta auditiva em 906 recém-nascidos sem indicadores de risco para deficiência auditiva e com apêndices pré-auriculares isolados (uni ou bilaterais) quanto a: prevalência de recém-nascidos com apêndices pré-auriculares; respostas de reflexo cócleo-palpebral; características das emissões otoacústicas; características do potencial evocado auditivo de tronco encefálico; e a incidência dessa causuística que apresente perda auditiva. Método: a identificação de indicadores de risco para deficiência auditiva foi realizada a partir da carteira do recém-nascido, do prontuário médico e de uma entrevista com os pais. Foram avaliados o meato acústico externo e a membrana timpânica através de otoscopia e espéculos auriculares. O reflexo cócleo-palpebral foi testado percutindo-se um agogô próximo ao recém-nascido. Pesquisa das emissões otoacústicas foi realizada com o aparelho ero scan etymotic research. Avaliou-se o potencial evocado auditivo do tronco encefálico. Resultado e discusssão: a prevalência de apêndices pré-auriculares foi de 1,1%. Todos apresentaram reflexo cócleo palpebral presente, passaram pelas EOA e o potencial evocado auditivo de tronco encefálico apresentou resposta eletrofisiológica dentro dos padrões de normalidade em todos os pacientes estudados. Conclusão: não houve correlação entre a perda auditiva e a presença de apêndices pré-auriculares

Introduction: pre-auricular appendages, together with other craniofacial malformations and temporal bone, are associated with hearing loss. Among the malformations of the auricle are the preauricular appendages, formed by skin and cartilage, and that can be present at any point between the tragus of the ear and the angle of the mouth, uni or bilateral. Objective: to evaluate the auditory response in 906 newborns without risk indicators for hearing loss and with isolated pre-auricular appendages (uni- or bilateral) for: prevalence of newborns with pre-auricular appendages; responses of cochlear-eyelid reflex; characteristics of otoacoustic emissions; characteristics of auditory brainstem evoked potential; and the incidence of this cause that presents hearing loss. Method: identification of risk indicators for hearing loss was carried out from the newborn's wallet, the medical record and the interview with the parents. The external acoustic meatus and the tympanic membrane were evaluated through otoscopy and atrial speculum. The cochlear-eyelid reflex was tested by percututing an agogot close to the newborn. Research on otoacoustic emissions was performed using the ero scan etymotic research apparatus. The auditory evoked potential of the brainstem was evaluated. Results and discussion: the prevalence of pre-auricular appendages was 1.1%. All of them presented a palpebral cochlear reflex present, passed through the OAE, and the auditory evoked potential of the brainstem presented an electrophysiological response within normality patterns in all patients studied. Conclusion: there was no correlation between hearing loss and the presence of pre-auricular appendages alone.

A lung image reconstruction from computed radiography images as a tool to tuberculosis treatment control

Background: Tuberculosis (TB) is an infectious lung disease with high worldwide incidence that severely compromises the quality of life in affected individuals. Clinical tests are currently employed to monitor pulmonary status and treatment progression. The present study aimed to apply a three-dimensional (3D) reconstruction method based on chest radiography to quantify lung-involvement volume of TB acute-phase patients before and after treatment. In addition, these results were compared with indices from conventional clinical exams to show the coincidence level. Methods: A 3D lung reconstruction method using patient chest radiography was applied to quantify lung-involvement volume using retrospective examinations of 50 patients who were diagnosed with pulmonary TB and treated with two different drugs schemes. Twenty-five patients were treated with Scheme I (rifampicin, isoniazid, and pyrazinamide), whereas twenty-five patients were treated with Scheme II (rifampicin, isoniazid, pyrazinamide, and ethambutol). Acute-phase reaction: Serum exams included C-reactive protein levels, erythrocyte sedimentation rate, and albumin levels. Pulmonary function was tested posttreatment. Results: We found strong agreement between lung involvement and serum indices pre- and posttreatment. Comparison of the functional severity degree with lung involvement based on 3D image quantification for both treatment schemes found a high correlation. Conclusions: The present 3D reconstruction method produced a satisfactory agreement with the acute-phase reaction, most notably a higher significance level with the C-reactive protein. We also found a quite reasonable coincidence between the 3D reconstruction method and the degree of functional lung impairment posttreatment. The performance of the quantification method was satisfactory when comparing the two treatment schemes. Thus, the 3D reconstruction quantification method may be useful tools for monitoring TB treatment. The association with serum indices are not only inexpensive and sensitive but also may be incorporated into the assessment of patients during TB treatment.(AU)

Festa, lazer e religião: o caso da festa de São João em Tupi, Piracicaba-SP / Festival, leisure and religion: the case of the St. John festival in Tupi, Piracicaba, SP

Essa pesquisa analisa duas das possibilidades inter-relacionadas da festa: lazer e religião. Tem por objetivos identificar os aspectos significativos da participação popular oportunizados pela “Festa de São João” em Tupi (distrito da cidade de Piracicaba, no interior do estado de São Paulo) e verificar a dimensão de lazer experimentado e proporcionado pelos que organizam e/ou participam ativamente desta festa. Trata-se de um estudo de caso, e a escolha da cidade se deu de forma não probabilística, seguindo critérios de representatividade e acessibilidade. Utilizou-se uma combinação das pesquisas bibliográfica, documental e de campo. As técnicas utilizadas foram: análise bibliográfica, análise de conteúdo, observação participante, com anotações em diário de campo, e entrevistas estruturadas. O estudo confirma que a festa é uma atividade de lazer e as análises indicam que há relações entre lazer e religião e que estas assumem várias formas.

The present research analyzes two inter-related possibilities involving the St. John Festival: leisure and religion. It aims at identifying the significant aspects of the popular participation provided by the “St. John Festival”, which takes place in Tupi (a district of the city of Piracicaba, in the countryside of São Paulo) and also at checking the dimension of leisure experienced and provided by those who organize or take active part in the festival. This is a case study and the city was chosen in a non-probabilistic way, following criteria of representativeness and accessibility. The work made use of a combination of literature review, documentary and field research. The techniques used were: literature analysis, content analysis, participant observation with the use of a field journal, and structured interviews. The study confirms that the festival is a leisure activity and analyses show that there are relations between leisure and religion and these can take over several forms.